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Related Experiment Videos

Parasitic diseases in immunocompromised hosts.

B Wong

    The American Journal of Medicine
    |March 1, 1984
    PubMed
    Summary

    The rise of acquired immunodeficiency syndrome (AIDS) necessitates renewed physician focus on protozoan and nematode infections in immunocompromised patients. This review covers diagnosis, treatment, and prevention strategies for these opportunistic diseases.

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    Area of Science:

    • Infectious Diseases
    • Immunology
    • Parasitology

    Background:

    • Protozoan and nematode infections were declining but have resurged due to the acquired immunodeficiency syndrome (AIDS) epidemic.
    • Patients with compromised host defenses are at increased risk for these opportunistic infections.
    • Physicians need to be re-familiarized with these diseases in abnormal hosts.

    Purpose of the Study:

    • To review the manifestations, diagnosis, treatment, and prevention of protozoan and nematode infections in immunocompromised patients.
    • To highlight the increased importance of these infections in the context of AIDS.
    • To summarize recent clinical experience with these infections in AIDS patients.

    Main Methods:

    • Review of clinical syndromes and current approaches to diagnosis, treatment, and prevention.
    • Summary of recent experience with infections in patients with AIDS at Memorial Sloan-Kettering Cancer Center.

    Main Results:

    • Opportunistic protozoan and nematode infections are significant concerns in patients with compromised immunity, particularly those with AIDS.
    • Specific organisms discussed include Pneumocystis carinii, Toxoplasma gondii, Strongyloides stercoralis, and Cryptosporidium species.
    • Recent data from AIDS patients provide valuable insights into managing these infections.

    Conclusions:

    • The resurgence of AIDS has re-emphasized the clinical importance of protozoan and nematode infections in immunocompromised individuals.
    • Familiarity with these diseases and current management strategies is crucial for physicians.
    • Continued vigilance and updated knowledge are necessary for effective patient care.

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