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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Deoxycorticosterone and 17-ketosteroids. Elevated levels in adult hypertensive patients
JAMA
|July 14, 1978
Abstract:
Plasma 11-deoxycorticosterone levels were manyfold elevated in three adult patients with hypertension and elevated urinary excretion levels of 17-ketosteroids but without Cushing's syndrome. Dexamethasone therapy resulted in suppression of these steroids and in improvement of blood pressure in two of the patients. A partial adrenal 11beta-hydroxylase deficiency appears to best explain these findings.
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