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Updated: May 7, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Complete recovery from hepatitis B and associated hemolysis in a patient with underlying T-cell deficiency
Abstract:
A 17-yr-old woman presented with acute hepatitis B. She had preexisting well-documented immune deficiency, clinically apparent as chronic mucocutaneous candidiasis, and recurrent severe viral infections. Life-threatening but spontaneously resolving Coombs-negative hemolysis complicated the recovery phase. Complete healing of the hepatitis with disappearance of hepatitis B surface antigen from serum and normal hepatitis B surface antibody and hepatitis B core antibody production occurred in spite of T-cell dysfunction.
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