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Updated: Jul 16, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Emergency transvenous ablation of atrioventricular conduction to control refractory atrial tachycardia
Insights
Refractory arrhythmias were treated with transvenous ablation of atrioventricular conduction. This urgent procedure successfully controlled tachycardia in two out of three patients, demonstrating a safe and effective treatment option.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Patients with refractory arrhythmias often fail to respond to conventional antiarrhythmic drugs and direct current cardioversion.
- Urgent investigation and treatment are critical for patients with persistent, life-threatening arrhythmias.
Observation:
- Three patients with refractory arrhythmias underwent urgent investigation.
- Two patients had unsuccessful direct current cardioversion attempts.
- Transvenous ablation of atrioventricular conduction was considered for these challenging cases.
Findings:
- A novel approach involving transvenous ablation of atrioventricular conduction was performed.
- A temporary ventricular pacing system was utilized alongside an electrode for recording His and atrial electrograms.
- A 270 watt-second shock delivered at maximal His potential successfully controlled tachycardia in two patients.
- The procedure was found to be without deleterious effects in all patients.
Implications:
- Transvenous ablation of atrioventricular conduction presents a viable and safe therapeutic option for refractory arrhythmias.
- This technique offers an alternative when standard treatments like antiarrhythmic drugs and cardioversion fail.
- Further research may explore optimizing shock parameters and patient selection for this ablation method.
Abstract:
Three patients were referred for urgent investigation and treatment of refractory arrhythmias. Each patient had failed to respond to antiarrhythmic drugs and in two patients direct current cardioversion was also unsuccessful. Transvenous ablation of atrioventricular conduction was therefore thought appropriate. With a temporary ventricular pacing system in situ, a second electrode was used to record His and atrial electrograms. A 270 watt-second shock was delivered through this lead when the His potential was maximized. The tachycardia was controlled in two patients and the procedure was without deleterious effects.
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