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Arrhythmias after coronary bypass surgery
British Heart Journal
|June 1, 1984
Summary
Atrial fibrillation is common after coronary artery bypass surgery. Beta-blocker therapy, like propranolol, can significantly reduce its occurrence, unlike digoxin.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Atrial fibrillation (AF) is a frequent complication following coronary artery bypass grafting (CABG).
- Understanding AF's incidence, causes, and prevention is crucial for patient outcomes.
Purpose of the Study:
- To investigate the incidence, causes, and prevention of atrial fibrillation after coronary bypass surgery.
- To evaluate the efficacy of digoxin and propranolol in preventing AF post-CABG.
Main Methods:
- Prospective study of 90 patients undergoing CABG.
- Bedside and ambulatory electrocardiographic monitoring.
- Randomized groups: control, digoxin, and propranolol.
Main Results:
- Control group: 27% incidence of atrial fibrillation.
- Propranolol reduced AF incidence to 14.8%; digoxin had no effect and increased ventricular extrasystoles.
- Myocardial ischemic time and bundle branch block correlated with AF occurrence.
Conclusions:
- Atrial fibrillation is common after CABG, potentially due to myocardial ischemia or hypothermic injury.
- Beta-blockade (propranolol) effectively reduces AF incidence post-CABG.
- Digoxin is not effective for AF prevention and may increase ventricular arrhythmias.