Visual (optokinetic), somesthetic and vestibular inputs to the frog cerebellum

Unitary response to visual (optokinetic), somesthetic (neck and limb) and vestibular stimulation were recorded from the Purkinje cell layer throughout most of the dorsal surface of the frog cerebellum. Simple spike activity in Purkinje cells and activity from cells without complex spikes were considered. Optokinetic responses (types I-III) were restricted to the dorsal rim and auricular lobes. Units were sensitive to very small velocity of optokinetic cylinder rotation (0.02-0.03 degrees/s) with peak sensitivity at about 1 degree/s. On the average an approximately linear relation of response amplitude to stimulus velocity was observed from 0.02 to 1 degree/s. The response progressively diminished above 1 degree/s to become very small at 30 degrees/s. Asymmetric response and silencing of firing during part of the cycle were nonlinearities observed with sinusoidal optokinetic stimulation in the range of 0.02-1 Hz, +/- 5-10 degrees (peak velocities 0.8-30 degrees/s). Somesthetic responses were recorded throughout most of the corpus cerebelli proper but the strongest input was to rostral regions. No somatotopic arrangement was found. Rather, convergence from more than one limb and neck was relatively common. Adaptation to successive cycles of stimulation was characteristic of somesthetic responses. Vestibular responses (type I-IV) were recorded throughout most of the explored area but the strongest input was to the dorsal rim and auricular lobes. From the analysis of unitary activity, the dorsal rim and auricular lobes are shown to be functionally linked to the vestibular and optokinetic systems whereas the explored part of the corpus is linked to the somesthetic and vestibular systems.