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Cincinnati Lipid Research Clinic.

C J Glueck, P M Laskarzewski, J A Morrison

    Progress in Clinical and Biological Research
    |January 1, 1984
    PubMed
    Summary
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    The Princeton School District Family Study documented how coronary heart disease (CHD) risk factors aggregate within families. However, it had limitations in collecting detailed environmental and family history data.

    Area of Science:

    • Cardiovascular epidemiology
    • Human genetics
    • Public health

    Background:

    • The Collaborative Lipid Research Clinic's Family Study faced limitations in environmental data collection.
    • Previous studies highlighted inadequacies in quantifying family history data.

    Purpose of the Study:

    • To assess the utility of the Princeton School District Family Study.
    • To document within-family aggregation of coronary heart disease (CHD) risk factors.

    Main Methods:

    • Analysis of data from the Princeton School District Family Study.
    • Focus on a biracial cohort with diverse economic backgrounds.

    Main Results:

    • The study successfully documented within-family aggregation of CHD risk factors.

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  • Identified limitations in gathering comprehensive environmental and family history data.
  • Conclusions:

    • The Princeton School District Family Study provided valuable insights into familial aggregation of CHD risk factors.
    • Future studies should improve data collection on environmental influences and family history.