Selective and nonselective shunts for variceal bleeding. A prospective study of 103 patients

Insights

For recurrent bleeding varices, nonoperative treatments are not definitive. An elective distal splenorenal shunt offers a better quality of life and is the preferred surgical option for managing variceal hemorrhage.

Area of Science:

  • Gastroenterology
  • Hepatology
  • Surgical Gastroenterology

Background:

  • Bleeding varices represent a serious complication of portal hypertension.
  • Nonoperative management and nonselective shunts have limitations in treating recurrent variceal hemorrhage.

Purpose of the Study:

  • To evaluate the efficacy of selective shunts compared to nonoperative means and nonselective shunts for recurrent variceal hemorrhage.
  • To establish the distal splenorenal shunt as the elective procedure of choice.

Main Methods:

  • Retrospective analysis of patient outcomes following various treatments for bleeding varices.
  • Comparison of complication rates, particularly encephalopathy, and survival between selective and nonselective shunts.

Main Results:

  • Nonoperative treatments are not definitive for recurrent variceal bleeding.
  • Selective shunts, specifically the distal splenorenal shunt, are associated with lower encephalopathy rates and improved quality of life.
  • Nonselective shunts have similar survival but higher encephalopathy rates, reserving them for specific emergency or complex cases.

Conclusions:

  • The elective distal splenorenal shunt is the optimal surgical treatment for recurrent variceal hemorrhage.
  • Shunt surgery, when well-planned, offers low mortality, long-term patency, and significant survival, remaining the gold standard.

Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...