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Updated: Sep 27, 2026

Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
Published on: March 12, 2019
Effect of gonadectomy and adrenalectomy on steroid hormone content in rat submaxillary gland
Abstract:
In male rats the adrenals appear to be a main source of progestagen in submaxillary glands, while in female rats the same is true for ovaries and adrenals. In both sexes certain amounts of progestagens were found in submaxillary glands up to 21 days after gonadectomy and adrenalectomy which might suggest that submaxillary glands possess the ability to synthesize these steroids. In contrast, however, almost negligible concentrations of androgens in submaxillary glands were observed in male rats beginning from 3 to 6 days after castration from which it may be concluded that no androgen producing ability is present in this tissue.
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