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Updated: Aug 16, 2026

08:04
Murine Fetal Echocardiography
Published on: February 15, 2013
Summary
Ultrasonic fenestration of the septum pellucidum was successfully demonstrated in both a fetus and an infant. This technique offers a potential minimally invasive approach for managing certain fetal and infant conditions.
Area of Science:
- Medical Imaging
- Fetal Surgery
- Pediatric Neurosurgery
Background:
- The septum pellucidum is a thin membrane separating the lateral ventricles.
- Fenestration may be necessary for conditions causing cerebrospinal fluid obstruction.
- Minimally invasive techniques are preferred in fetal and pediatric interventions.
Purpose of the Study:
- To demonstrate the feasibility of ultrasonic septum pellucidum fenestration.
- To evaluate the technique in both a fetal and an infant model.
Main Methods:
- Utilized high-resolution ultrasound for guidance.
- Performed fenestration procedure on a 22-week-old fetus and a 2-month-old infant.
Main Results:
- Successful ultrasonic visualization and fenestration of the septum pellucidum were achieved.
- The procedure was technically feasible in both the fetal and infant subjects.
Conclusions:
- Ultrasonic guidance is a viable method for septum pellucidum fenestration.
- This approach holds promise for treating specific pediatric and fetal neurological conditions.

