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[Snake bites and coagulation disorders].

E Stahel, G A Marbet

    Schweizerische Medizinische Wochenschrift
    |July 12, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Snakebites from hemotoxic snakes (crotalids, viperids) can cause severe coagulation disorders. Prompt antivenin treatment is crucial for rapid recovery of coagulation factors.

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    Area of Science:

    • Toxicology
    • Herpetology
    • Clinical Medicine

    Background:

    • This study examines cases of hemotoxic snakebites in the Basle area over six years.
    • Focuses on patients who own snakes and have experienced bites from potentially dangerous species.

    Observation:

    • Eight snake owners were hospitalized for 12 bites from hemotoxic snakes (crotalids, viperids).
    • Two patients showed no envenomation signs; ten experienced local cytotoxic effects like edema and bruising.
    • Six cases presented systemic hemotoxic envenomation, including decreased coagulation factor activity.

    Findings:

    • Complete defibrination occurred in four patients; overt bleeding (urological) was seen in two with additional thrombocytopenia.
    • No central nervous system or gastrointestinal bleeding complications were reported.

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  • Antivenin administration in three patients led to coagulation recovery within 24 hours.

    • Implications:

    • Highlights the potential severity of hemotoxic snakebites, even in non-endemic areas.
    • Underscores the effectiveness of antivenin in reversing coagulopathy and the importance of timely medical intervention.
    • Suggests that while local and systemic effects are common, severe bleeding complications may be less frequent but require vigilant management.