Related Experiment Video

Updated: Aug 28, 2026

Ex Vivo Culture of Primary Human Fallopian Tube Epithelial Cells
11:46

Ex Vivo Culture of Primary Human Fallopian Tube Epithelial Cells

Published on: May 9, 2011

Adenocarcinoma of the fallopian tube

B E Amendola, J LaRouere, M A Amendola

    Surgery, Gynecology & Obstetrics
    |September 1, 1983
    PubMed

    Insights

    This study on fallopian tube cancer found that pelvic irradiation after surgery improved survival rates for early-stage disease. Early detection of secondary tumors was also noted in some patients.

    Area of Science:

    • Gynecologic Oncology
    • Radiation Oncology
    • Cancer Epidemiology

    Background:

    • Fallopian tube carcinoma is a rare malignancy within the female reproductive system.
    • Adenocarcinoma of the fallopian tube presents unique diagnostic and therapeutic challenges.

    Purpose of the Study:

    • To analyze survival outcomes for patients with fallopian tube adenocarcinoma.
    • To evaluate the impact of postoperative pelvic irradiation on survival rates.
    • To report the incidence of secondary primary tumors in this patient cohort.

    Main Methods:

    • Retrospective review of 34 patients treated for fallopian tube adenocarcinoma over 27 years.
    • Analysis of patient data including treatment modalities and survival.
    • Assessment of the effect of specific radiation doses on patient outcomes.

    Main Results:

    • Overall two-year and five-year survival rates were 52% and 20%, respectively.
    • Eight out of 34 patients (23.5%) were diagnosed with early second primary tumors.
    • Postoperative pelvic irradiation exceeding 50 Gray (Gy) in five weeks correlated with improved five-year survival for localized disease.

    Conclusions:

    • Postoperative pelvic irradiation may enhance survival for fallopian tube cancer patients with localized disease.
    • The occurrence of secondary primary tumors warrants consideration in the work-up of fallopian tube cancer.
    • Further research is needed to optimize treatment strategies for this rare cancer.

    More Related Videos

    Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection08:09

    Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

    Published on: July 25, 2017

    An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses07:03

    An Efficient Method for Extracting Human Fallopian Tube Epithelia for Single-cell Analyses

    Published on: March 28, 2025

    Related Concept Videos

    Ovaries01:26

    Ovaries

    The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
    On the ovarian surface, a layer of cuboidal...
    Ovarian Cycle01:27

    Ovarian Cycle

    The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
    Uterine Tubes01:16

    Uterine Tubes

    The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
    Appendicitis01:19

    Appendicitis

    Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...