[Modification of suprapubic prostatectomy using a biological gluing technic].

Area of Science:

• Urology
• Surgical Innovation
• Biomaterials

Background:

• Suprapubic transvesical prostatectomy can involve significant postoperative blood loss.
• Effective hemostasis and wound healing are crucial for patient recovery.
• Novel surgical adjuncts are sought to improve outcomes in prostatectomy procedures.

Purpose of the Study:

• To evaluate the efficacy of fibrin glue in reducing blood loss during suprapubic transvesical prostatectomy.
• To assess the impact of fibrin glue application on postoperative complications and hospital stay.
• To determine the safety profile of using fibrin glue in this surgical context.

Main Methods:

• Fibrin glue, composed of fibrinogen cryoprecipitate, thrombin solution, and factor XIII concentrate, was prepared.
• The fibrin glue was applied to an absorbable collagen velour scaffold.
• This scaffold was placed in the prostatic bed following prostatectomy.
• A control group undergoing the same procedure without fibrin glue was used for comparison.

Main Results:

• Significantly smaller postoperative blood loss was observed in the fibrin glue group compared to the control group.
• The use of fibrin glue led to fewer blood transfusions required.
• Disturbances in wound healing were reduced, and the postoperative hospital stay was shortened.
• No negative consequences associated with the fibrin glue technique were reported.

Conclusions:

• Fibrin glue application is an effective method for reducing blood loss in suprapubic transvesical prostatectomy.
• This surgical gluing technique improves patient recovery by minimizing complications and hospital stay.
• Fibrin glue represents a safe and beneficial adjunct for prostatectomy surgery.