Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Binodal disease: diseased sinus node and atrioventricular block].

M Fromer, L Kappenberger, W Steinbrunn

    Zeitschrift Fur Kardiologie
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.

    Molecular psychiatry·2016
    Same author

    Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.

    Translational psychiatry·2015
    Same author

    Copy number variation in schizophrenia in Sweden.

    Molecular psychiatry·2014
    Same author

    Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample.

    Molecular psychiatry·2013
    Same author

    [Implantable cardiac defibrillator (ICD): basics and present clinical guidelines].

    Revue medicale suisse·2013
    Same author

    [Percutaneous closure of left atrial appendage: a new hope for patients with atrial fibrillation?].

    Revue medicale suisse·2013

    This study investigated sinus node function in patients with AV block and AV conduction in patients with sick sinus syndrome. Persistence of abnormal function after atropine suggests organic disease, impacting treatment considerations for sick sinus syndrome.

    Area of Science:

    • Electrophysiology
    • Cardiology

    Context:

    • Atrioventricular (AV) conduction disturbances are common in sick sinus syndrome (SSS).
    • Sinus node function (SNF) in patients with AV block is less understood.
    • Electrophysiological testing is crucial for diagnosing these conditions.

    Purpose:

    • To evaluate SNF in patients with high-degree AV block.
    • To assess AV conduction in patients with SSS.
    • To differentiate between vagal effects and organic disease.

    Summary:

    • Electrophysiological tests were performed on 30 patients with AV block and 15 with SSS.
    • Measurements included sinus node recovery time (SNRT), corrected SNRT (cSNRT), and Wenckebach point.
    • Tests were repeated after atropine administration to assess vagal influence.

    Related Experiment Videos

    Impact:

    • Persistent abnormalities after vagolysis suggest organic binodal disease in approximately 10% of patients.
    • Findings highlight the importance of considering AV conduction delays in SSS patients undergoing atrial pacing.
    • Distinguishing vagal tone from organic disease aids in appropriate patient management.