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In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
Septic arthritis caused by Kingella kingae
American Journal of Diseases of Children (1960)
|October 1, 1983
Summary
Kingella kingae, a rare pathogen, commonly causes bone and joint infections. This organism is sensitive to penicillin and responds well to treatment, despite diagnostic challenges.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Background:
- Kingella kingae is a gram-negative coccobacillus, typically found in the human oropharynx.
- It is infrequently recognized as a human pathogen.
Observation:
- This study reviews nine cases of Kingella kingae infections, predominantly bone and joint infections.
- Diagnostic challenges include slow growth in cultures and negative Gram stains of initial aspirates.
Findings:
- Kingella kingae infections primarily affect bones and joints.
- The organism demonstrates consistent sensitivity to penicillin and other common antibiotics.
- All reported patients showed a positive response to antibiotic treatment.
Implications:
- Kingella kingae should be considered in cases of bone and joint infections, especially when initial cultures are negative.
- Prompt diagnosis and treatment with appropriate antibiotics lead to favorable outcomes.
- Further research into the pathogenicity and diagnostics of Kingella kingae is warranted.
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