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Esophageal involvement in Behcet's disease.

S Mori, A Yoshihira, H Kawamura

    The American Journal of Gastroenterology
    |September 1, 1983
    PubMed
    Summary

    Esophageal involvement in Behcet

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    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Pathology

    Background:

    • Behcet's disease is a rare multisystemic vasculitis.
    • Esophageal involvement is an exceptionally uncommon manifestation of Behcet's disease, with limited case reports.
    • Understanding the clinical, morphological, and histological features of esophageal Behcet's disease is crucial for diagnosis and management.

    Observation:

    • Five new cases of esophageal Behcet's disease were analyzed.
    • Esophageal lesions were more prevalent in males with incomplete Behcet's disease.
    • Elevated erythrocyte sedimentation rate and C-reactive protein levels were noted.

    Findings:

    • The mid-esophagus was the most frequently affected site.
    • Morphological presentations varied, including erosions, ulcers, esophagitis, and stenosis, lacking a unique pattern.
    • Histology showed lymphocytic or neutrophilic infiltration; vasculitis was infrequent.

    Implications:

    • This study expands the understanding of esophageal Behcet's disease with five new cases.
    • The diverse morphological features necessitate considering Behcet's disease in esophageal ulcerations, especially in affected demographics.
    • Further research into the pathogenesis and specific diagnostic markers for esophageal Behcet's disease is warranted.

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