Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Determinants of systemic zero-flow arterial pressure.

M J Brunner, A S Greene, K Sagawa

    The American Journal of Physiology
    |September 1, 1983
    PubMed
    Summary

    Zero-flow arterial pressure is influenced by venous pressure, hematocrit, and vasomotor tone. These findings challenge the vascular waterfall model for understanding arteriovenous pressure differences.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Expression of CD44 variant isoforms, CD44v3 and CD44v6, are associated with prognosis in nasopharyngeal carcinoma.

    The Journal of laryngology and otology·2016
    Same author

    Sharing best practices in teaching biomedical engineering design.

    Annals of biomedical engineering·2013
    Same author

    Production of IL-8 and the other cytokines by T cell clones established from the ocular fluid of patients with Behçet's disease.

    Ocular immunology and inflammation·2012
    Same author

    Measurement of vascular density.

    Methods in molecular medicine·2011
    Same author

    Consecutive national surveys of ABO-incompatible blood transfusion in Japan.

    Vox sanguinis·2009
    Same author

    Characterization of a local renin-angiotensin system in rat gingival tissue.

    Journal of periodontology·2009

    Area of Science:

    • Cardiovascular Physiology
    • Hemodynamics

    Background:

    • The vascular waterfall model is often used to explain the pressure gradient at zero flow.
    • Understanding factors affecting zero-flow arterial pressure is crucial for cardiovascular research.

    Purpose of the Study:

    • To investigate the impact of venous pressure, hematocrit, and vasomotor tone on zero-flow arterial pressure.
    • To evaluate the validity of the vascular waterfall concept in this context.

    Main Methods:

    • Isolated carotid sinuses in pentobarbital-anesthetized dogs under total cardiac bypass.
    • Manipulation of intrasinus pressure, systemic venous pressure, and hematocrit.
    • Administration of vasoactive agents (epinephrine, hexamethonium, papaverine).

    Main Results:

    • Zero-flow arterial pressure was significantly higher when venous pressure increased.
    • Epinephrine, hexamethonium, and papaverine altered zero-flow arterial pressure.
    • Reduced hematocrit led to significant changes in zero-flow arterial pressure.

    Conclusions:

    • Zero-flow arterial pressure is modulated by venous pressure, hematocrit, and vasomotor tone.
    • The vascular waterfall model, as literally interpreted, is not fully supported by these findings.

    Related Experiment Videos