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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Acute pityriasis rubra pilaris in the child. Apropos of 4 cases]
Abstract:
Four cases of Pityriasis Rubra Pilaris of an acute type have been studied in three to six year old children. In three cases the disease occurred after an infection; in one out of these three cases this infection was serologically confirmed as being german measles. In the beginning, only the face is affected or the face and other part of the body. The rash looks like scarlet fever and the folicular papules appear only during the second stage. The dermatosis usually spreads within a month (from twenty days to two months) and covers the whole body without becoming erythrodermic. Then clinical picture is typical of Pityriasis Rubra Pilaris. There are no associated symptoms and no hypo-vitaminemia A is evidenced. The evolution is self limited with a spontaneous regression within three months, and there is no recurrence. These cases are similar to the classical juvenile Pityriasis Rubra Pilaris type III of Griffiths, but they keep their own particularities as far as acute evolution and good prognosis are concerned.
Insights
Acute Pityriasis Rubra Pilaris in children presents with a distinctive rash, often following infection. This form shows a rapid onset and spontaneous resolution within months, indicating a favorable prognosis.
Area of Science:
- Dermatology
- Pediatrics
Context:
- Pityriasis Rubra Pilaris (PRP) is a rare chronic skin disorder.
- Juvenile PRP has several subtypes, with Type III being a classical form.
- Acute presentations in children are less commonly documented.
Purpose:
- To describe the clinical characteristics and outcomes of four pediatric cases of acute Pityriasis Rubra Pilaris.
- To differentiate this acute form from classical juvenile PRP.
- To highlight the distinct clinical course and prognosis.
Summary:
- Four children aged 3-6 years presented with acute PRP, with onset following infection in three cases (one confirmed German measles).
- Initial facial rash evolved to a generalized dermatosis resembling scarlet fever, with follicular papules appearing in the second stage.
- The condition resolved spontaneously within three months without recurrence, showing no associated symptoms or vitamin A deficiency.
Impact:
- This study identifies a distinct acute variant of juvenile Pityriasis Rubra Pilaris.
- It emphasizes the favorable prognosis and self-limiting nature of this specific presentation.
- Findings contribute to a better understanding of PRP heterogeneity in pediatric populations.
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