Hemopoietic responses of LPS-unresponsive C3H/HeJ mice to salmonella infection

Effects of Salmonella enteritidis infection on hemopoietic stem cells were examined in LPS-unresponsive C3H/HeJ mice. The salmonella infection increased pluripotent stem cells (CFUs) and granulocyte-macrophage progenitor cells (CFUc) in the spleen and decreased these hemopoietic stem cells in the bone marrow. These responses seemed to be specific to salmonella infection and not due to biological activities of LPS.