Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mathematical studies of complement activation.

M A Garrigue, J P Muh, P Bardos

    Clinica Chimica Acta; International Journal of Clinical Chemistry
    |August 15, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Developing and validating a practical decision support tool (DST) for biomass selection on marginal land.

    Journal of environmental management·2014
    Same author

    Apolipoprotein E genotype and plasma lipid levels in Caucasian diabetic patients.

    Diabetes & metabolism·2006
    Same author

    Changes in plasma triacylglycerol concentrations after sequential lunch and dinner in healthy subjects.

    Diabetes & metabolism·2005
    Same author

    [Is procalcitonin able to help in pediatric appendicitis diagnosis?].

    Annales de chirurgie·2005
    Same author

    SMN1 gene study in three families in which ALS and spinal muscular atrophy co-exist.

    Neurology·2002
    Same author

    Recipient TNFRSF6 (FAS) gene polymorphism and acute renal allograft rejection.

    Transplantation proceedings·2002
    Same journal

    Chemometric profiling reveals selective circulating bile acid remodeling in Alzheimer's disease.

    Clinica chimica acta; international journal of clinical chemistry·2026
    Same journal

    Serum sialic acid is independently associated with cerebrovascular atherosclerotic stenosis severity and total vascular burden: A retrospective cohort study.

    Clinica chimica acta; international journal of clinical chemistry·2026
    Same journal

    Measurement of low-density lipoprotein cholesterol and other circulating lipids in Brazil: a systematic literature review.

    Clinica chimica acta; international journal of clinical chemistry·2026
    Same journal

    Reference intervals for venous blood gas measurement in a healthy Chinese population.

    Clinica chimica acta; international journal of clinical chemistry·2026
    Same journal

    Multiplex methylation marker analysis for ctDNA detection in liquid biopsies from anal cancer patients: an HPV-independent approach.

    Clinica chimica acta; international journal of clinical chemistry·2026
    Same journal

    Development and validation of patient-based exponentially weighted moving average quality control models for three antipsychotic drugs and their metabolites by LC-MS/MS.

    Clinica chimica acta; international journal of clinical chemistry·2026
    See all related articles

    This study quantifies complement activation pathways using kinetic analysis. The classical and alternative pathways were differentiated, revealing their distinct contributions to immune responses.

    Area of Science:

    • Immunology
    • Biochemistry

    Background:

    • The complement system is a crucial part of innate immunity.
    • Understanding the kinetics of complement activation is essential for diagnosing immune disorders.

    Purpose of the Study:

    • To kinetically differentiate the classical and alternative complement pathways.
    • To quantify the contribution of specific activators to complement activation.

    Main Methods:

    • Hemolytic assays were employed to monitor complement activation.
    • Mathematical analysis of kinetic data was used to model pathway contributions.

    Main Results:

    • Kinetic curves revealed two distinct phases, corresponding to the classical and alternative pathways.
    • The relative participation of inulin, zymosan, and aggregated immunoglobulins was determined.

    Related Experiment Videos

    Conclusions:

    • Kinetic analysis provides a robust method for dissecting complement pathway activation.
    • This approach allows for the precise assessment of activator roles in the complement cascade.