Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mammographic and pathological correlations in a breast screening programme.

G W Stamp, G H Whitehouse, I W McDicken

    Clinical Radiology
    |September 1, 1983
    PubMed
    Summary

    Mammography screening of 5000 women identified suspicious lesions. While microcalcifications and mass lesions were common biopsy indicators, specific features like irregular calcifications and ill-defined masses correlated with malignancy, guiding better breast cancer diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Relationship among eye and muzzle temperatures measured using digital infrared thermal imaging and vaginal and rectal temperatures in hair sheep and cattle.

    Journal of animal science·2014
    Same author

    Ten-year follow-up of skin-sparing mastectomy followed by immediate breast reconstruction.

    The British journal of surgery·2012
    Same author

    Impact of national guidelines on family history breast cancer surveillance.

    Scottish medical journal·2011
    Same author

    Pancreatic-derived pathfinder cells enable regeneration of critically damaged adult pancreatic tissue and completely reverse streptozotocin-induced diabetes.

    Rejuvenation research·2011
    Same author

    A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial.

    British journal of cancer·2010
    Same author

    Workplace-based assessment as an educational tool: guide supplement 31.2 - viewpoint.

    Medical teacher·2009

    Area of Science:

    • Radiology
    • Pathology
    • Oncology

    Background:

    • Mammography is a key screening tool for breast cancer detection.
    • Accurate interpretation of mammographic findings is crucial for timely diagnosis and patient management.

    Purpose of the Study:

    • To correlate mammographic findings with histopathological results in a screening population.
    • To identify specific radiological features indicative of malignancy versus benign breast disease.

    Main Methods:

    • Retrospective analysis of mammograms from 5000 women aged 35-60 undergoing screening.
    • Biopsy performed on suspicious areas, with subsequent histological examination.
    • Correlation of mammographic features (microcalcification, mass characteristics, architectural distortion, spiculation) with biopsy outcomes.

    Related Experiment Videos

    Main Results:

    • Biopsy rate was 2.58% for suspicious lesions, with 18.6% confirming malignancy.
    • Rounded microcalcifications were common biopsy indications but benign; irregular calcifications suggested benign disease.
    • Ill-defined masses with microcalcification/spiculation were often malignant; rounded masses were mostly benign.
    • Architectural distortion and spiculation were significant indicators of malignancy.

    Conclusions:

    • Specific mammographic features, including calcification morphology and mass characteristics, aid in differentiating benign from malignant breast lesions.
    • Understanding these radiological-pathological correlations can optimize biopsy decisions and improve breast cancer screening efficacy.
    • Spiculation is a strong, though not absolute, predictor of malignancy in mammography.