Glycogenolysis in the fasting dog

Glycogen concentrations were determined in liver-biopsy specimens which were taken from four dogs during five consecutive days of fasting. It was found that maximal depletion of liver glycogen occurred between the second and the third day. Starvation-induced glycogenolysis was much slower in the dog than in men and rats. Fuel fluxes are discussed and it is tentatively concluded that in the fasting dog larger amounts of glycerol are available for gluconeogenesis than in other species.