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Spontaneous arteriovenous plasma separation.

H K Stummvoll, H Graf, A Luger

    Critical Care Medicine
    |October 1, 1983
    PubMed
    Summary
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    Spontaneous arteriovenous membrane plasma separation offers a safe and effective method for plasmapheresis (PP) without needing blood pumps. This technique, suitable for ICU settings, can be combined with continuous arteriovenous hemofiltration.

    Area of Science:

    • Nephrology
    • Critical Care Medicine
    • Cardiovascular Surgery

    Background:

    • Plasmapheresis (PP) is a crucial extracorporeal therapy.
    • Traditional PP often requires specialized equipment and monitoring.
    • Minimally invasive techniques are sought for intensive care unit (ICU) applications.

    Purpose of the Study:

    • To evaluate the feasibility and safety of spontaneous arteriovenous membrane plasma separation.
    • To assess the utility of this method in an ICU environment.
    • To determine its compatibility with concurrent therapies like continuous arteriovenous hemofiltration.

    Main Methods:

    • Utilized spontaneous arteriovenous membrane plasma separation via femoral artery and vein cannulation.
    • Employed the Seldinger technique for catheter insertion.

    Related Experiment Videos

  • Leveraged the natural arteriovenous pressure gradient, eliminating the need for blood pumps or extensive monitoring.

    • Main Results:

    • Successfully performed 44 plasmapheresis therapies across eight patients.
    • No complications were reported during the procedures in the ICU.
    • Demonstrated successful integration with continuous arteriovenous hemofiltration.

    Conclusions:

    • Spontaneous arteriovenous membrane plasma separation is a safe and effective plasmapheresis method.
    • This technique is well-suited for the ICU setting due to its simplicity and lack of need for specialized monitoring.
    • The method shows promise for combined use with other renal replacement therapies.