Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reactions during work shift among cotton mill workers.

R Rylander, P Haglind, B T Butcher

    Chest
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pre-eclampsia, solid-fuel cooking, and magnesium.

    Indoor air·2015
    Same author

    Comment on 'Possible pro-carcinogenic association of endotoxin on lung cancer among Shanghai women textile workers'.

    British journal of cancer·2014
    Same author

    Fungi in homes--how do we measure?

    Indoor air·2014
    Same author

    Airborne fungal cell fragments in homes in relation to total fungal biomass.

    Indoor air·2012
    Same author

    Lung cancer risk in subjects exposed to organic dust: an unexpected and surprising story.

    Thorax·2012
    Same author

    In vitro and in vivo reactivity to fungal cell wall agents in sarcoidosis.

    Clinical and experimental immunology·2011

    Cotton mill workers experienced reduced lung function (FEV1) and increased blood neutrophils on Mondays, linked to airborne dust and endotoxin exposure. Immunologic reactions beyond Type 1 may be involved in respiratory responses.

    Area of Science:

    • Occupational Health
    • Environmental Medicine
    • Immunology

    Background:

    • Cotton mill workers are exposed to airborne dust and bacterial endotoxins.
    • Respiratory symptoms and lung function changes are common in this population.
    • The role of specific immunological responses in cotton dust-induced lung issues requires further investigation.

    Purpose of the Study:

    • To assess the impact of occupational exposure to cotton dust on lung function and blood neutrophil counts in mill workers.
    • To investigate the correlation between airborne dust/endotoxin levels and physiological changes.
    • To evaluate the utility of the radioallergosorbent (RAST) test in assessing allergic responses to cotton dust.

    Main Methods:

    • Measurements of lung function (FEV1) and blood neutrophils in 13 cotton mill workers across the work week.

    Related Experiment Videos

  • Quantification of airborne respirable dust and bacterial endotoxin using elutriators and personal samplers.
  • Radioallergosorbent (RAST) testing on serum and plasma samples to assess allergic sensitization.

    • Main Results:

    • Significant reductions in FEV1 and elevated blood neutrophils were observed on Mondays at specific exposure levels.
    • Blood neutrophil changes correlated with endotoxin levels, while FEV1 decreases were specific to Monday.
    • RAST test results were low and showed no correlation with FEV1 or changes during the work shift.

    Conclusions:

    • Occupational exposure to cotton dust, particularly endotoxins, can acutely affect lung function and inflammatory markers in workers.
    • The findings suggest that non-Type 1 immunologic mechanisms may play a crucial role in the respiratory effects of cotton dust exposure.
    • Further research into alternative immunological pathways is warranted to understand and mitigate occupational lung diseases in textile workers.