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[Postextrasystolic sinus responses after autonomic blockade in patients with sinus node dysfunction].

L Szatmáry, C Barnay, G Hanvic

    Giornale Italiano Di Cardiologia
    |January 1, 1983
    PubMed
    Summary

    Postextrasystolic responses in sinus node dysfunction diagnosis are controversial. This study reveals abnormal responses increase in patients with abnormal intrinsic heart rate after autonomic blockade, impacting diagnosis.

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    Area of Science:

    • Cardiology
    • Electrophysiology
    • Autonomic Nervous System

    Context:

    • Sinus node dysfunction diagnosis relies on electrophysiological studies.
    • Postextrasystolic responses interpretation remains debated.
    • Autonomic nervous system influences sinoatrial node function.

    Purpose:

    • To investigate the significance of postextrasystolic responses in patients with sinus node dysfunction.
    • To evaluate the impact of autonomic blockade on these responses.
    • To correlate findings with intrinsic heart rate.

    Summary:

    • Programmed atrial stimulation was performed in 54 patients with sinoatrial disorder before and after autonomic blockade.
    • Two responses were analyzed: sinoatrial conduction times and chaotic patterns.

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  • Abnormal response prevalence increased from 70% to 90% in patients with abnormal intrinsic heart rate after blockade, mainly due to chaotic patterns.

    • Impact:

    • Findings suggest postextrasystolic responses, particularly chaotic patterns after autonomic blockade, are significant indicators in diagnosing sinus node dysfunction.
    • The study highlights the role of autonomic balance and intrinsic electrophysiological integrity in sinoatrial node function.
    • Results aid in refining diagnostic criteria for sinoatrial disorders.