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Related Experiment Videos

Bacteremia after endoscopic injection sclerosis.

L B Cohen, M A Korsten, E J Scherl

    Gastrointestinal Endoscopy
    |August 1, 1983
    PubMed
    Summary

    Endoscopic injection sclerotherapy for esophageal varices frequently causes bacteremia (50% of cases). This transient bloodstream infection is higher than routine endoscopy, suggesting antibiotic prophylaxis may be needed for some patients.

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    Area of Science:

    • Gastroenterology
    • Infectious Diseases

    Background:

    • Esophageal varices pose a significant bleeding risk.
    • Endoscopic injection sclerotherapy is a common treatment for esophageal varices.
    • Minor complications like fever and bacteremia have been reported with sclerotherapy.

    Purpose of the Study:

    • To prospectively evaluate the frequency of bacteremia after endoscopic injection sclerotherapy for esophageal varices.
    • To compare the incidence of bacteremia between sclerotherapy and routine upper endoscopy.

    Main Methods:

    • Prospective study design.
    • Blood cultures were obtained post-sclerotherapy.
    • Comparison group underwent upper gastrointestinal endoscopy without sclerosis.

    Main Results:

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    • Bacteremia was detected in 14 out of 28 procedures (50%).
    • No bacteremia occurred in the control group undergoing routine endoscopy (p < 0.05).
    • Bacteremia was transient and not associated with clinical complications.

    Conclusions:

    • Injection sclerotherapy for esophageal varices is associated with a significantly higher incidence of bacteremia compared to routine endoscopy.
    • Alpha-hemolytic streptococcus was the most common organism, likely an oropharyngeal contaminant.
    • Antibiotic prophylaxis may be warranted for selected patients undergoing this procedure.