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[Malignant melanoma: prognostic evaluation using correlation coefficients].

C Kühnl-Petzoldt, H Berger, H Wiebelt

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |August 1, 1983
    PubMed
    Summary

    Malignant melanoma tumor thickness correlates with growth, invasion, type, and cell type. However, patient sex, ulceration, and diameter independently impact survival, irrespective of tumor thickness.

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    Area of Science:

    • Dermatology and Oncology
    • Biostatistics

    Context:

    • Malignant melanoma exhibits complex interrelationships between clinical and histological features.
    • Understanding these correlations is crucial for accurate prognostic assessment.

    Purpose:

    • To investigate the correlations between various clinical and histological variables of malignant melanoma.
    • To determine which factors independently influence patient survival.

    Summary:

    • Tumor thickness is correlated with exophytic growth, invasion level, Clark's melanoma type, and predominant cell type.
    • These factors do not affect survival in melanomas of identical thickness.
    • Patient sex, ulceration, and melanoma diameter are independent of tumor thickness and significantly impact survival.
    • Melanoma site of origin correlates with patient sex but not tumor thickness, with controversial survival implications.

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    Impact:

    • Provides a clearer understanding of prognostic indicators in malignant melanoma.
    • Highlights the independent prognostic significance of sex, ulceration, and diameter.
    • Informs clinical decision-making and patient counseling regarding melanoma prognosis.