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Pseudomembranous colitis associated with changes in an ileal conduit
Abstract:
A case of antibiotic associated pseudomembranous colitis following total cystectomy is reported, in which there was involvement of the ileal conduit. The small bowel remaining in situ was uninvolved. Bacteriological studies revealed Clostridium difficile and the toxin in both colon and ileal conduit. Relevant publications concerning pathogenesis are discussed, in relation to the unusual site described in this case. Epidemiological evidence is reviewed which suggests that isolation of patients with pseudomembranous colitis is a logical course of action.
Insights
This case study reports antibiotic-associated pseudomembranous colitis affecting an ileal conduit after total cystectomy. Clostridium difficile and its toxin were identified in the colon and conduit, highlighting an unusual site of infection.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Surgical Oncology
Background:
- Antibiotic-associated pseudomembranous colitis (PMC) is typically confined to the colon.
- Total cystectomy involves bladder removal, often with urinary diversion like an ileal conduit.
- The ileal conduit, a surgically created channel, is an unusual site for PMC.
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