Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Indomethacin-responsive episodic cluster headache.

D P Geaney

    Journal of Neurology, Neurosurgery, and Psychiatry
    |September 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment.

    The British journal of psychiatry : the journal of mental science·1998
    Same author

    Haloperidol enhances latent inhibition in visual tasks in healthy people.

    Psychopharmacology·1997
    Same author

    Intravenous administration of haloperidol to healthy volunteers: lack of subjective effects but clear objective effects.

    Journal of psychopharmacology (Oxford, England)·1997
    Same author

    Antipsychotic drug effects in a model of schizophrenic attentional disorder: a randomized controlled trial of the effects of haloperidol on latent inhibition in healthy people.

    Biological psychiatry·1996
    Same author

    Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia.

    Biological psychiatry·1992
    Same author

    5-[3H]hydroxytryptamine and [3H]lysergic acid diethylamide binding to human platelets.

    Methods in enzymology·1992
    Same journal

    Clinical outcomes of conservative, endovascular and microsurgical management of unruptured giant intracranial aneurysms: 3-year follow-up of the prospective, multinational Giant Intracranial Aneurysm Registry.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Global epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Diagnostic accuracy of a two-cut-off approach using the FAQ/MMSE ratio and FAQ for clinical preselection of patients for anti-amyloid therapy.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Cancer risk and mortality in patients with multiple sclerosis in Finland: a retrospective population-based cohort study.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

    Journal of neurology, neurosurgery, and psychiatry·2026
    Same journal

    Characteristics and outcomes in electric scooter-related traumatic brain injuries in Helsinki.

    Journal of neurology, neurosurgery, and psychiatry·2026
    See all related articles

    Indomethacin dramatically relieved chronic, severe cluster headaches unresponsive to other treatments. A double-blind trial confirmed indomethacin

    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Cluster headaches are a severe primary headache disorder.
    • Episodic cluster headaches can significantly impact quality of life.

    Observation:

    • A patient presented with a 34-year history of severe episodic cluster headaches.
    • Headaches occurred up to twenty times daily during cluster periods.
    • Conventional therapies were ineffective for this patient's headaches.

    Findings:

    • Indomethacin provided dramatic relief from the cluster headaches.
    • A subsequent double-blind, placebo-controlled trial confirmed the efficacy of indomethacin.
    • Indomethacin is a potent nonsteroidal anti-inflammatory drug (NSAID).

    Implications:

    Related Experiment Videos

    • Indomethacin represents a highly effective treatment option for severe, refractory cluster headaches.
    • This finding may guide future therapeutic strategies for cluster headache management.
    • Further research into NSAID mechanisms in cluster headache is warranted.