Prophylaxis of hepatitis A with immune globulin

Hepatitis has been outstanding as a military disease. Although it was not recognized as a commonplace illness in civilian populations until 35 years ago, hepatitis has been a problem in all major wars during the last two centuries. Much of the knowledge of this disease has been obtained by investigation of outbreaks in military populations. The military importance of hepatitis during World War II led to studies of this disorder which defined it as a distinct clinical entity and delineated both the epidemiology and its mode of transmission.