Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Persistent hyperparathyroidism caused by incomplete parathyroid resection and a hyperfunctioning parathyroid

A M Spiegel, R W Downs, A Santora

    JAMA
    |October 14, 1983
    PubMed
    Summary

    Familial primary hyperparathyroidism can persist due to retained hyperplastic parathyroid tissue and autografts. Successful treatment involves locating and removing this tissue from multiple sites, including the forearm.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases.

    Respiratory research·2024
    Same author

    A phase 2 study of MK-5442, a calcium-sensing receptor antagonist, in postmenopausal women with osteoporosis after long-term use of oral bisphosphonates.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Self-reported calcium use in a cohort of postmenopausal women receiving osteoporosis therapy: results from POSSIBLE US™.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Spontaneous Intracellular Calcium Oscillations and G(s) α Subunit Expression are Inversely Correlated with Secretory Granule Content in Pituitary Cells.

    Journal of neuroendocrinology·2011
    Same author

    Persistence and switching patterns among women with varied osteoporosis medication histories: 12-month results from POSSIBLE US.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2010
    Same author

    Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2009

    Area of Science:

    • Endocrinology
    • Surgical Oncology

    Background:

    • Familial primary hyperparathyroidism presents a complex clinical challenge.
    • Persistent hypercalcemia can result from incomplete initial surgical management.

    Observation:

    • A case involving persistent hypercalcemia was observed in familial primary hyperparathyroidism.
    • The hypercalcemia was attributed to residual hyperplastic parathyroid tissue in the neck and mediastinum, alongside a hyperfunctioning autograft in the forearm.

    Findings:

    • Successful management necessitated precise parathyroid localization techniques.
    • Surgical resection of ectopic parathyroid tissue from the neck, mediastinum, and forearm was crucial for normalizing calcium levels.

    Implications:

    • Autotransplantation of parathyroid tissue should be judiciously considered, reserved for situations where complete parathyroidectomy is anticipated.

    Related Experiment Videos

  • This case underscores the importance of thorough surgical assessment and localization in managing recurrent or persistent hyperparathyroidism.