A food pelleter for experimental diets for rats

Food pellets for an experimental diet for laboratory rats were produced for long-term nephrotoxicity study using a modified, commercially available pasta machine. This method eliminated the disadvantages of powdered diets and provided the advantages of pelleted diets at low production cost. A commercially available, pelleted diet was pulverized, the test agent and water added, and the mixture repelletized. No special feeding equipment was required because the repelletized diet was fed in standard lid-type feeders. It was not necessary to sterilize the diet.