[Experimental studies of adipose tissue necrosis in acute tryptic pancreatitis]

Necrosis of adipose tissue in acute pancreatitis is characterized by hydrolysis of triglycerides yielding glycerin and fatty acids, part of which are converted to alcali salts. Earlier studies in fatty necrosis of pancreatic tissue had delt mainly with calcium. In our study on acute pancreatitis in Wistar rats it could be shown, that especially during the initial phase by far; after 48 hours however calciums salts prevail. This finding can be explained, if one assumes, that the easily soluble alcali salts are converted to the almost insoluble calcium salt within a certain time in the tissue.