Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Computer tomography in determining lung density for irradiation planning].

K Merkle, O N Spasokukotskaia, S E Evdonin

    Meditsinskaia Radiologiia
    |September 1, 1983
    PubMed
    Summary

    Accurate lung density determination is crucial for thoracic tumor irradiation planning. CT scans during quiet breathing provide representative lung density values for radiation therapy, with individual adjustments recommended when necessary.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A phase I study of bendamustine hydrochloride administered day 1+2 every 3 weeks in patients with solid tumours.

    British journal of cancer·2007
    Same author

    Treatment of bendamustine and prednisone in patients with newly diagnosed multiple myeloma results in superior complete response rate, prolonged time to treatment failure and improved quality of life compared to treatment with melphalan and prednisone--a randomized phase III study of the East German Study Group of Hematology and Oncology (OSHO).

    Journal of cancer research and clinical oncology·2006
    Same author

    Regression of brain metastases from breast carcinoma after chemotherapy with bendamustine.

    Journal of cancer research and clinical oncology·2002
    Same author

    Weekly administration of bendamustine: a phase I study in patients with advanced progressive solid tumours.

    Annals of oncology : official journal of the European Society for Medical Oncology·2000
    Same author

    Repeated administration of short infusions of bendamustine: a phase I study in patients with advanced progressive solid tumours.

    Journal of cancer research and clinical oncology·2000
    Same author

    Bendamustine as salvage treatment in patients with advanced progressive breast cancer: a phase II study.

    Journal of cancer research and clinical oncology·1998

    Area of Science:

    • Medical Physics
    • Radiotherapy
    • Diagnostic Imaging

    Background:

    • Accurate lung density is critical for effective thoracic tumor irradiation planning.
    • Computed Tomography (CT) is a primary imaging modality for radiotherapy planning.
    • Variability in lung density necessitates precise measurement for optimal treatment.

    Purpose of the Study:

    • To determine representative lung density values for irradiation planning in thoracic tumors.
    • To investigate the impact of different breathing states on lung density measurements.
    • To establish guidelines for CT acquisition protocols for accurate lung density assessment.

    Main Methods:

    • Analysis of 118 CT sections from patients undergoing thoracic imaging.
    • Measurement of mean lung density during quiet breathing, deep breathing, and full expiration.

    Related Experiment Videos

  • Assessment of the range and variability of lung density values across individuals and within lung sections.

    • Main Results:

    • Mean lung density during quiet breathing was 0.252 +/- 0.118 g/cm3.
    • Lung density varied significantly with breathing state: 0.162 +/- 0.022 g/cm3 (deep breathing) and 0.282 +/- 0.050 g/cm3 (full expiration).
    • A wide range of lung densities (0.119–0.441 g/cm3) was observed during quiet breathing, with variations also noted within individual CT sections.

    Conclusions:

    • CT scans for radiotherapy planning should be performed during quiet, uninterrupted breathing to obtain representative lung density.
    • Individual lung density assessment is recommended when measured values deviate significantly for isodose calculation.
    • Standardized CT protocols and consideration of patient-specific lung density are essential for precise radiation therapy.