Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Olfactory functioning in temporal lobectomy patients.

B Eskenazi, W S Cain, R A Novelly

    Neuropsychologia
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Determinants of organophosphorus pesticide urinary metabolite levels in pregnant women from the CHAMACOS cohort.

    The Science of the total environment·2022
    Same author

    Prenatal phthalate exposure and 8-isoprostane among Mexican-American children with high prevalence of obesity.

    Journal of developmental origins of health and disease·2016
    Same author

    Dichlorodiphenyltrichloroethane exposure and anogenital distance in the Venda Health Examination of Mothers, Babies and their Environment (VHEMBE) birth cohort study, South Africa.

    Andrology·2016
    Same author

    An assessment of dioxin exposure across gestation and lactation using a PBPK model and new data from Seveso.

    Environment international·2016
    Same author

    Higher measured moisture in California homes with qualitative evidence of dampness.

    Indoor air·2015
    Same author

    Determinants of manganese levels in house dust samples from the CHAMACOS cohort.

    The Science of the total environment·2014
    Same journal

    Identifying Networks within an fMRI Multivariate Searchlight Analysis.

    Neuropsychologia·2026
    Same journal

    Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

    Neuropsychologia·2026
    Same journal

    Deficient processing of regularity violations during visuospatial neglect: a visual mismatch negativity study.

    Neuropsychologia·2026
    Same journal

    Seeing is believing: mental imagery amplifies moral, emotional, and motivational responding to mentally constructed hypothetical events.

    Neuropsychologia·2026
    Same journal

    From Past Recall to Future Projection: What Does Verb Tense Production Reveal About Mental Time Travel in Alzheimer's disease?

    Neuropsychologia·2026
    Same journal

    Eye Movement Measures of Word-Level and Text-Level Fluency in Disordered Reading: A Comparison of Schizophrenia and Dyslexia.

    Neuropsychologia·2026
    See all related articles

    Temporal lobe epilepsy surgery impairs olfactory functioning. Patients undergoing unilateral temporal lobectomy showed deficits in odor discrimination and memory, despite normal basic smell sensitivity.

    Area of Science:

    • Neuroscience
    • Olfactory research
    • Epilepsy research

    Background:

    • Intractable epilepsy often necessitates surgical intervention, specifically temporal lobectomy.
    • The olfactory system's processing is intricately linked to temporal lobe structures.
    • The impact of temporal lobectomy on olfactory function requires detailed investigation.

    Purpose of the Study:

    • To evaluate olfactory functioning in patients following unilateral temporal lobectomy.
    • To compare olfactory performance between epilepsy patients and healthy controls.
    • To identify specific deficits in olfactory processing after temporal lobectomy.

    Main Methods:

    • Seventeen patients with unilateral temporal lobectomy for epilepsy were assessed.
    • Forty-six healthy individuals served as controls.

    Related Experiment Videos

  • A comprehensive battery of olfactory tests was administered, including quality discrimination, memory, odor-source matching, and verbal identification.

    • Main Results:

    • Patients with temporal lobectomy performed significantly worse than controls across all olfactory tests.
    • No significant performance differences were observed between dominant and non-dominant temporal lobectomy groups.
    • Impairments were noted in odor quality discrimination and recognition memory.

    Conclusions:

    • Unilateral temporal lobectomy for intractable epilepsy leads to widespread olfactory deficits.
    • These deficits persist despite preserved absolute olfactory sensitivity.
    • Impaired quality discrimination and attention lapses may explain the observed olfactory dysfunction.