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Interaction between manganese and phenobarbital on hexobarbital hypnosis in the male rat
Research Communications in Chemical Pathology and Pharmacology
|July 1, 1983
Abstract:
Pretreatment of male rats with phenobarbital markedly decreases while treatment with manganese prolongs the duration of hexobarbital hypnosis in male rats. When both agents were administered simultaneously, the manganese-induced prolongation of hexobarbital was prevented.