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Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye
Science (New York, N.Y.)
|October 14, 1983
Abstract:
Carcinoma cells and normal epithelial cells differ in the mitochondrial retention of a permeant cationic compound, rhodamine 123. The possibility of utilizing this difference in carcinoma chemotherapy was investigated. Rhodamine 123 exhibited anticarcinoma activity in mice, and this activity was potentiated by 2-deoxyglucose.
