Richter's syndrome--an indication for lymph node biopsy in chronic lymphocytic leukaemia. A case report

A patient suffering from typical chronic lymphocytic leukaemia (CLL) developed a rapidly fatal high-grade lymphoma (Richter's syndrome). In cases of CLL Richter's syndrome must be distinguished from coexistent Hodgkin's disease and prolymphocytic transformation. The prognosis is dismal but not hopeless if the condition is treated early. Lymph node biopsy is essential for diagnosis and treatment.