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Trazodone and priapism.

M Scher, J N Krieger, S Juergens

    The American Journal of Psychiatry
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Trazodone, an antidepressant, has been linked to priapism cases since 1982. This report details one of the severe priapism cases requiring surgical intervention.

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    Area of Science:

    • Pharmacology
    • Urology

    Background:

    • Trazodone, an antidepressant with anxiolytic properties, has been available since 1982.
    • Priapism is a prolonged erection, often requiring medical intervention.

    Observation:

    • Eleven cases of priapism associated with Trazodone use have been reported in the US.
    • Five of these cases necessitated surgical procedures.

    Findings:

    • The authors present a case of Trazodone-induced priapism that required surgical management.
    • This highlights a significant adverse effect of Trazodone.

    Implications:

    • Clinicians should be aware of the risk of priapism when prescribing Trazodone.
    • Further research may be needed to understand the mechanism and incidence of Trazodone-related priapism.