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Human pulmonary granulomas caused by Chrysosporium parvum var. crescens (Emmonsia crescens)

Insights

Autopsy revealed multiple lung nodules containing adiaspores. These were identified as Chrysosporium parvum var. crescens, a fungus causing adiaspiromycosis.

Area of Science:

  • Medical Mycology
  • Pulmonary Pathology

Background:

  • Adiaspiromycosis is a granulomatous pulmonary disease caused by the inhalation of fungal spores.
  • Chrysosporium parvum is a dimorphic fungus with two varieties, C. parvum var. parvum and C. parvum var. crescens.

Purpose of the Study:

  • To identify the etiological agent in multiple lung nodules found during an autopsy.
  • To document a case of adiaspiromycosis in a human.

Main Methods:

  • Autopsy examination of lung tissue.
  • Microscopic identification of fungal elements within lung nodules.

Main Results:

  • Multiple pulmonary nodules were observed in the lungs.
  • Adiaspores, characteristic of Chrysosporium parvum var. crescens, were identified within these nodules.

Conclusions:

  • The lung nodules were caused by Chrysosporium parvum var. crescens.
  • This case highlights the potential for adiaspiromycosis to manifest as multiple pulmonary nodules.

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