[Pathomorphological changes in the kidneys in acute intestinal infections in children]

Morphological lesions of the kidneys in 59 autopsy observations of acute intestinal infections in children were studied. The greatest disorders were found in patients with the toxico-septic form of intestinal infections complicated by the development of bacterial shock. Impairments of the microcirculatory hemodynamics accompanied by dystrophic and necrotic changes in the epithelium of the tubules underlie renal lesions. These changes directly depend on the duration of bacterial shock. With a protracted course of bacterial shock acute renal insufficiency develops. In other forms of the disease renal lesions are insignificant and do not constitute a serious part of tanatogenesis.