Related Experiment Video

Updated: Aug 8, 2026

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
05:49

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

Published on: November 29, 2024

Phosphono-platelet activating factor I. Synthesis of 1-O-hexadecyl-2-O-acetyl-glyceryl-3-(2-trimethyl

M C Moschidis, C A Demopoulos, L G Kritikou

    Chemistry and Physics of Lipids
    |July 1, 1983
    PubMed

    Abstract:

    The total synthesis of 1-O-alkyl-2-acetyl-3-glyceryl-(2-trimethyl ammoniummethyl) phosphonate, the phosphono analogue of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, is described. The phosphonolipid shows much lower activity than the phospholipid stimulating serotonin release from rabbit platelets.

    More Related Videos

    Analyzing Platelet Subpopulations by Multi-color Flow Cytometry
    08:04

    Analyzing Platelet Subpopulations by Multi-color Flow Cytometry

    Published on: June 10, 2025

    Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
    04:37

    Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation

    Published on: May 23, 2025

    Related Experiment Videos

    Last Updated: Aug 8, 2026

    Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
    05:49

    Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

    Published on: November 29, 2024

    Analyzing Platelet Subpopulations by Multi-color Flow Cytometry
    08:04

    Analyzing Platelet Subpopulations by Multi-color Flow Cytometry

    Published on: June 10, 2025

    Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation
    04:37

    Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation

    Published on: May 23, 2025

    Related Concept Videos

    Phosphoinositides and PIPs01:42

    Phosphoinositides and PIPs

    Phosphoinositides are a group of phospholipids containing a glycerol backbone with two fatty acid chains and a phosphate attached to a myoinositol sugar ring. The inositol head group extends into the cytoplasm, where it is modified by adding phosphate groups to form phosphatidylinositol phosphates or PIPs.
    Different phosphoinositides are synthesized and recruited on the cytosolic face of the plasma membrane. The localization of specific phosphoinositides concentrated in separate membrane...

    Articles linked to this work by shared authors, journal, and citation graph.

    Effect of Robola and Cabernet Sauvignon extracts on platelet activating factor enzymes activity on U937 cells.

    Food chemistry·2014

    Vitamin D receptor activators upregulate and rescue podocalyxin expression in high glucose-treated human podocytes.

    Nephron. Experimental nephrology·2013

    Effects of highly active antiretroviral therapy on platelet activating factor metabolism in naive HIV-infected patients: ii) study of the abacavir/lamivudine/efavirenz HAART regimen.

    International journal of immunopathology and pharmacology·2012

    Atherosclerosis regression study in rabbits upon olive pomace polar lipid extract administration.

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2009

    The implication of platelet activating factor in cancer growth and metastasis: potent beneficial role of PAF-inhibitors and antioxidants.

    Infectious disorders drug targets·2009

    Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration.

    Digestive diseases and sciences·2006

    Lipid headgroup-dependent interactions of an isovanillin derivative with DPPC and DPPS Langmuir monolayers.

    Chemistry and physics of lipids·2026

    Understanding charged polymer-lipid interactions in model membranes revealed by EPR and solid-state NMR: Implications for membrane protein studies.

    Chemistry and physics of lipids·2026

    Sodium-induced lipid bilayer phase transition for an ester lipid and phase transition resistance for an ether branched-lipid.

    Chemistry and physics of lipids·2026

    Cleavable carbosilane dendrimers modulate the thermodynamical properties of DMPC/DPPG lipid membrane and conformation of human serum albumin.

    Chemistry and physics of lipids·2026

    Analysis of glycosyldiacylglycerols produced by the zoonotic pathogen Streptococcus suis.

    Chemistry and physics of lipids·2026

    The impact of avobenzone and oxybenzone on fibroblast and keratinocyte membranes. Searching for the role of lipids in the effect of UV filters on skin cells.

    Chemistry and physics of lipids·2026

    Multi-target neuroprotective mechanisms of epigallocatechin-3-gallate (EGCG) in stroke: from molecular pathways to nanomedicine delivery and clinical translation.

    Frontiers in pharmacology·2026

    MurNAc-Based Electrophilic Inhibitors of O-Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation.

    Chemistry (Weinheim an der Bergstrasse, Germany)·2026

    Self-Assembled Dansyl-Based Chiroptical L/D-Valine and L/D-Phenylalanine Conjugate for Hg(II) Detection and Catalytic Conversion of Carbon Dioxide.

    Chemistry (Weinheim an der Bergstrasse, Germany)·2026

    γ-aminobutyric acid type A receptors modulate neurosteroid binding to the voltage-dependent anion channel.

    Acta chimica Slovenica·2026

    An Engineered Supramolecular Pathway for Enhanced Electrochemiluminescence.

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

    Design and baseline characteristics of the CagriSema cardiovascular outcomes trial (REDEFINE 3).

    American heart journal·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us