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Cinnarizine in the prophylaxis of car sickness in children
Insights
Cinnarizine effectively prevents car sickness in children, with 81% finding it good or excellent. This medication offers a better alternative for travel sickness with minimal side effects like drowsiness.
Area of Science:
- Pediatrics
- Pharmacology
- Gastroenterology
Background:
- Car sickness (motion sickness) is a common condition affecting children.
- Prophylactic treatment is often sought to prevent travel sickness symptoms.
Purpose of the Study:
- To evaluate the efficacy and tolerance of cinnarizine for preventing car sickness in children.
- To compare cinnarizine's effectiveness against previous travel sickness medications.
Main Methods:
- An open-label study involving 79 children susceptible to car sickness.
- Children received a 15 mg cinnarizine tablet 2 hours before travel, with additional doses as needed.
- Efficacy and tolerance were assessed through children's and doctors' evaluations.
Main Results:
- 81% of children rated cinnarizine as 'good' or 'excellent' for car sickness prevention.
- 69% of children who previously used other medications found cinnarizine superior.
- Vomiting occurred in only 4% of children, and drowsiness in 14%.
Conclusions:
- Cinnarizine demonstrates high efficacy and good tolerance as a prophylactic treatment for car sickness in children.
- The study suggests cinnarizine is a favorable option for managing pediatric travel sickness.
- Participating physicians indicated a willingness to prescribe cinnarizine based on study outcomes.
Abstract:
An open study was carried out in 79 children known to be susceptible to car sickness to assess the efficacy and tolerance of cinnarizine used prophylactically. Each child received one 15 mg cinnarizine tablet 2 hours before a long car journey and a further half-tablet every 8 hours thereafter, if required. The results of the children's assessments indicated that 81% considered the preparation either 'good' or 'excellent' and 69% of the 68 who had previously received other medication for travel sickness rated it 'better' or 'much better'. Only 4% of the children vomited and only 14% felt sleepy or drowsy. All but 3 of the 52 doctors who participated were prepared to give cinnarizine again to their charges based on the experience of this study.