[Electron microscopic studies of experimental staphylococcal infections in mice as chemotherapeutic models]

Study of ultrastructural changes in the brain and renal tissues has shown that both intracerebral and intraperitoneal administration of staphylococcus in low infecting doses leads to the development in the brain and renal tissues of acute purulent inflammation, with a dramatic growth of infectious process and involvement of all parts of the organs under consideration. The presence in the brain tissues and in its meninges of inflammatory pyonecrotic foci might attest to the necrotic purulent encephalomeningitis, whereas the presence in the cortex and renal medullary substance of histiolymphocytic infiltration and foci of necrosis might be evidence of necrotic glomerulonephritis of bacterial etiology.