Prenatal diagnosis and management of omphalocele

The prenatal diagnosis of omphalocele by real-time sonography is important for intrauterine and neonatal management and prognosis. The prognosis and mortality rate is determined rather by the presence of serious associated anomalies such as cardiovascular and chromosomal defects, than by the omphalocele itself. Obstetric management in the presence of an omphalocele should therefore include immediate amniocentesis for chromosomal analysis and ultrasonic scanning of the fetus for other structural abnormalities. The obstetric management should be coordinated by the neonatologist and pediatric surgeon to ensure timely and optimal care of the infant.