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Related Experiment Video

Updated: May 1, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
07:10

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy

Published on: June 18, 2020

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Experience with transjugular liver biopsy.

H J Bull, I T Gilmore, R D Bradley

    Gut
    |November 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

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    Transjugular liver biopsy using a modified needle achieved a 97% adequate specimen rate with rare complications. Ultrasonic cleaning reduced fever, making it a safe option for select patients.

    Area of Science:

    • Hepatology
    • Interventional Radiology
    • Gastroenterology

    Background:

    • Transjugular liver biopsy is an alternative to percutaneous biopsy, particularly in patients with coagulopathy or ascites.
    • A modified needle technique aims to improve specimen adequacy and reduce complications.
    • Assessing the safety and efficacy of this modified transjugular approach is crucial.

    Purpose of the Study:

    • To describe the results of transjugular liver biopsies performed with a modified needle.
    • To evaluate specimen adequacy and complication rates associated with the technique.
    • To compare the modified transjugular approach with traditional percutaneous biopsy.

    Main Methods:

    • 193 transjugular liver biopsies were performed using a modified needle.

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  • Specimen adequacy was assessed.
  • Complications, including bleeding and fever, were recorded.
  • Ultrasonic cleaning of the needle was employed to reduce post-procedure fever.

    • Main Results:

    • An adequate tissue specimen was obtained in 97% of cases.
    • Complications were rare, with two instances of bleeding due to liver capsule puncture.
    • Post-procedure fever was reduced following ultrasonic cleaning of the needle.
    • The technique was deemed safe but technically demanding.

    Conclusions:

    • The modified transjugular liver biopsy technique is safe and effective, yielding high specimen adequacy.
    • Ultrasonic needle cleaning effectively reduces post-procedural fever.
    • While suitable for selected patients, percutaneous biopsy remains the preferred method for most cases due to its generally lower technical difficulty.