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The initial glycosylation of the Sindbis virus membrane proteins
Progress in Clinical and Biological Research
|January 1, 1978
Abstract:
The mechanism by which the membrane proteins of Sindbis virus are initially glycosylated during growth of the virus in chick cells was studied. The experiments suggest strongly that the 2 viral glycoproteins are glycosylated before release from the polysome and that this glycosylation involves transfer of a large, 1,800 dalton oligosaccharide to the polypeptide chains. The donor of the oligosaccharide is most probably a lipid.