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Hemoglobin Maputo: a new beta-chain variant (alpha 2 beta 2 47 (CD6) Asp replaced by Tyr) in combination with
Hemoglobin
|January 1, 1983
Abstract:
During a routine hematological investigation, a slowly-moving hemoglobin variant was detected in a 2-year-old child from Maputo (Mozambique) in combination with hemoglobin S. Structural studies carried out by HPLC demonstrated a previously unreported amino acid substitution, beta 47 (CD6) Asp replaced by Tyr. The new hemoglobin variant has been named hemoglobin Maputo.