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Related Experiment Videos

"Anaerobic threshold": problems of determination and validation.

M P Yeh, R M Gardner, T D Adams

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |October 1, 1983
    PubMed
    Summary

    The anaerobic threshold (AT) is difficult to detect invasively using lactate levels. Noninvasive methods show significant variability, making them unsuitable for clinical use in exercise physiology.

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    Area of Science:

    • Exercise Physiology
    • Sports Medicine
    • Biochemistry

    Background:

    • The anaerobic threshold (AT) is a popular concept in exercise physiology.
    • Current noninvasive AT detection methods are subjective.
    • Invasive AT validation often overlooks lactate differences across blood sources.

    Purpose of the Study:

    • To investigate the reliability of invasive and noninvasive methods for detecting the anaerobic threshold.
    • To compare arterial and venous lactate responses during incremental exercise.
    • To assess the inter-observer variability in noninvasive AT determination.

    Main Methods:

    • Eight healthy subjects performed incremental exercise tests on a bicycle ergometer.
    • Simultaneous arterial and venous blood samples were collected for lactate analysis.

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  • Noninvasive gas exchange data were measured using a breath-by-breath system.
  • Four exercise physiologists independently determined AT from gas response data.

    • Main Results:

    • No clear threshold phenomenon in lactate accumulation was observed.
    • Arterial lactate increased continuously during exercise.
    • Venous lactate rise lagged behind arterial lactate by approximately 1.5 minutes.
    • Noninvasive AT determination exhibited significant inter-observer variability (average range 16%).

    Conclusions:

    • Invasive lactate measurements (arterial and venous) are not suitable for detecting AT.
    • Noninvasive gas response determination of AT is unreliable due to high reviewer variability.
    • Current methods for AT detection lack clinical applicability.