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Gyriform calcification after herpes simplex virus encephalitis.

L Ketonen, M L Koskiniemi

    Journal of Computer Assisted Tomography
    |December 1, 1983
    PubMed
    Summary
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    Bilateral gyriform calcification, mimicking Sturge-Weber syndrome, can occur after herpes simplex virus encephalitis. This rare finding, identified via computed tomography (CT) scans, is presented as a unique case study.

    Area of Science:

    • Neurology
    • Radiology
    • Infectious Diseases

    Background:

    • Intracranial calcification is a recognized complication of various neurological conditions.
    • Sturge-Weber syndrome is a neurocutaneous disorder characterized by distinctive vascular malformations and often intracranial calcification.
    • Herpes simplex virus (HSV) encephalitis is a severe brain infection that can lead to diverse neurological sequelae.

    Observation:

    • A rare case of a patient presenting with bilateral gyriform intracranial calcification is described.
    • The calcification pattern closely simulated that typically seen in Sturge-Weber syndrome.
    • The patient's history revealed a preceding episode of herpes simplex virus encephalitis.

    Findings:

    • Computed tomography (CT) scans demonstrated bilateral, gyriform calcification in the cerebral hemispheres.

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  • The calcification was attributed as a sequela of the prior HSV encephalitis.
  • This specific pattern of calcification post-HSV encephalitis has not been previously reported in the literature.

    • Implications:

    • This case expands the spectrum of known intracranial calcification patterns associated with viral encephalitis.
    • Radiologists and neurologists should consider infectious etiologies, particularly HSV encephalitis, in the differential diagnosis of intracranial calcification mimicking Sturge-Weber syndrome.
    • Further research may elucidate the precise mechanisms underlying gyriform calcification post-encephalitis.